Domain Bacteria
High Gram-Positive - Actinobacteria

Mycobacterium tuberculosis

The High Gram-Positive (or Actinobacteria) are a large group of non-mobile, spore-forming bacteria.

Most live in soil, playing a crucial role in the decomposition of organic materials.


But other High Gram-Positives are pathogens causing immense harm to humanity. They are resposible for tuberculosis, leprosy, diptheria and even acne. Worse, they continue to grow resistant to penicillin and other antibiotics.

  • Mycobacteria cause tuberculosis and leprosy.
  • Bifidobacteria have a natural and symbiotic relationship with humans as intestinal flora.
  • Streptomycetes are soil bacteria with complex biochemistry. They produce antibiotics in clinical use.
  • Corynebacteria causes respiratory diseases like diphtheria.
  • Propionibacteria cause acne.
  • Actinomyces colonize gums and teeth, often causing disease.

The older name Actinomycetes refers to the braching filaments some High Gram-Positives form, which resemble the mycelia threads of the unrelated Fungi.

DNA chemistry distinguishes the High Gram-Positives differ from the Low Gram-Positives.